Daniel H Palmer Selected Research

NUC-1031

1/2021	A Phase Ib Study of NUC-1031 in Combination with Cisplatin for the First-Line Treatment of Patients with Advanced Biliary Tract Cancer (ABC-08).
6/2020	NUC-1031/cisplatin versus gemcitabine/cisplatin in untreated locally advanced/metastatic biliary tract cancer (NuTide:121).

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Daniel H Palmer Research Topics

Disease

25	Neoplasms (Cancer) 04/2024 - 10/2002
18	Pancreatic Neoplasms (Pancreatic Cancer) 03/2023 - 01/2007
15	Hepatocellular Carcinoma (Hepatoma) 03/2022 - 12/2004
10	Biliary Tract Neoplasms (Biliary Tract Cancer) 01/2022 - 04/2010
9	Adenocarcinoma 04/2024 - 07/2012
7	Cholangiocarcinoma 01/2022 - 04/2010
5	Fatigue 01/2021 - 08/2015
5	Carcinoma (Carcinomatosis) 01/2021 - 01/2010
4	Gallbladder Neoplasms (Gallbladder Cancer) 01/2022 - 04/2010
4	Neutropenia 01/2021 - 07/2007
4	Disease Progression 01/2021 - 08/2015
4	Colorectal Neoplasms (Colorectal Cancer) 12/2019 - 07/2004
3	Liver Neoplasms (Liver Cancer) 09/2021 - 05/2004
3	Breast Neoplasms (Breast Cancer) 01/2007 - 12/2004
2	Rectal Neoplasms (Rectal Cancer) 06/2021 - 01/2016
2	Nausea 01/2021 - 12/2019
2	Diarrhea 01/2021 - 12/2019
2	Thrombocytopenia (Thrombopenia) 01/2021 - 01/2017
2	Infections 01/2021 - 04/2010
2	Hypertension (High Blood Pressure) 01/2017 - 08/2015
1	Febrile Neutropenia 01/2021
1	COVID-19 01/2021
1	Thrombosis (Thrombus) 01/2021
1	Acute Kidney Injury (Acute Renal Failure) 01/2021
1	Hypersensitivity (Allergy) 01/2020
1	Vomiting 12/2019
1	Hand-Foot Syndrome 01/2019
1	Margins of Excision 01/2019
1	Urinary Bladder Neoplasms (Bladder Cancer) 04/2017
1	Gastrointestinal Diseases (Functional Gastrointestinal Disorders) 01/2017
1	Abdominal Pain (Pain, Abdominal) 01/2017
1	Neoplasm Metastasis (Metastasis) 02/2016
1	Bile Duct Neoplasms (Bile Duct Cancer) 07/2012
1	Germ Cell and Embryonal Neoplasms (Germ Cell Tumor) 10/2008
1	Neoplasm Micrometastasis 07/2007

Drug/Important Bio-Agent (IBA)

17	Gemcitabine FDA Link 11/2021 - 01/2007
8	Sorafenib (BAY 43-9006)FDA Link 01/2022 - 12/2008
6	Fluorouracil (Carac)FDA LinkGeneric 11/2021 - 09/2010
6	Cisplatin (Platino)FDA LinkGeneric 01/2021 - 07/2007
5	Capecitabine (Xeloda)FDA Link 01/2022 - 03/2016
5	Leucovorin (Folinic Acid)FDA Link 01/2021 - 09/2010
4	Biomarkers (Surrogate Marker)IBA 03/2023 - 01/2015
4	BilirubinIBA 04/2021 - 12/2016
3	AlbuminsIBA 04/2021 - 12/2016
3	CD40 Ligand (CD40L)IBA 01/2020 - 01/2010
2	Proteins (Proteins, Gene)FDA Link 03/2023 - 01/2018
2	enzalutamideIBA 03/2022 - 09/2021
2	pembrolizumabIBA 01/2022 - 01/2022
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 09/2021 - 08/2015
2	NUC-1031IBA 01/2021 - 06/2020
2	Oxaliplatin (Eloxatin)FDA LinkGeneric 01/2021 - 03/2019
2	AntigensIBA 01/2020 - 01/2020
2	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 01/2020 - 03/2016
2	brusatolIBA 01/2019 - 01/2018
2	cediranib (AZD2171)IBA 01/2018 - 08/2015
2	LigandsIBA 03/2010 - 01/2010
2	ProdrugsIBA 07/2004 - 05/2004
2	EnzymesIBA 07/2004 - 05/2004
1	ProgranulinsIBA 04/2024
1	naphthalenediimideIBA 03/2023
1	Cytidine DeaminaseIBA 11/2021
1	Messenger RNA (mRNA)IBA 11/2021
1	Alanine Transaminase (SGPT)IBA 01/2021
1	TransferasesIBA 01/2021
1	RNA (Ribonucleic Acid)IBA 01/2020
1	SirtuinsIBA 01/2020
1	LuciferasesIBA 12/2019
1	fisogatinibIBA 12/2019
1	Irinotecan (Camptosar)FDA LinkGeneric 03/2019
1	Collagen Type I (Type I Collagen)IBA 11/2018
1	Immune Checkpoint InhibitorsIBA 01/2018
1	Keratin-18 (Keratin 18)IBA 01/2018
1	GranulinsIBA 01/2018
1	Histone Deacetylase InhibitorsIBA 09/2017
1	entinostat (MS 275)IBA 09/2017
1	OsteopontinIBA 04/2017
1	Tyrosine Kinase InhibitorsIBA 01/2017
1	(N- Ac- His(1)- Nle(17)- Arg(20,21)- Ala(26))- vasoactive intestinal peptideIBA 01/2017
1	Erlotinib Hydrochloride (CP 358,774)FDA Link 01/2017
1	nintedanibIBA 01/2017
1	vandetanib (ZD6474)IBA 01/2017
1	Interleukin-6 (Interleukin 6)IBA 03/2016
1	VaccinesIBA 03/2016
1	C-Reactive ProteinIBA 03/2016
1	Equilibrative Nucleoside Transporter 1IBA 01/2014
1	Matrix Metalloproteinases (MMPs)IBA 03/2010
1	Metalloproteases (Metalloproteinases)IBA 03/2010

Therapy/Procedure

25	Therapeutics 04/2024 - 10/2002
16	Drug Therapy (Chemotherapy) 12/2022 - 10/2002
6	Adjuvant Chemotherapy 11/2019 - 09/2010
3	Neoadjuvant Therapy 06/2021 - 07/2007
3	Immunotherapy 01/2020 - 04/2005
3	Radiotherapy 01/2020 - 10/2002
2	Ligation 01/2020 - 03/2010
1	Preoperative Exercise 06/2021
1	Microspheres (Microsphere) 01/2020
1	Intravenous Infusions 01/2017
1	Combination Drug Therapy (Combination Chemotherapy) 03/2016
1	Chemoprevention 02/2016
1	Ovariectomy (Oophorectomy) 01/2007